click for larger image from the 1996 Symposium
SCIENTIFIC PROGRAMME
PLENARY LECTURES
MONDAY, JANUARY 8
Morning
10:00 - 11:00 David G.I. Kingston
Department of Chemistry
Virginia Tech
Blacksburg, VA 24061-0212
U S A
TITLE: Fun and Games with Taxol: New and Old Reactions of
a Complex Natural Product.
11:10 - 12:10 Chris Abell
Department of Chemistry
University of Cambridge
Lensfield Road
Cambridge CB2 1EW
England
TITLE: Mechanistic Studies on Biosynthetic Enzymes
Afternoon
2:00 - 3:00 J -L. Wolfender
Institut De Pharmacognosie et
Phytochimie
University of Lausanne
BEO. CH-1915
Lausanne
Switzerland
TITLE: Strategies in the Search for New Bioactive Plant
Constituents.
TUESDAY, JANUARY 9
Morning
9:00 - 10:00 William F. Reynolds
Department of Chemistry
University of Toronto
Toronto, Ontario
Canada M5S 1A1
TITLE: Multi-Dimensional NMR Studies of Natural and Synthetic
Products
10:25 - 11:25 Mugio Nishizawa
Faculty of Pharmaceutical Sciences
Tokushima Bunri University
Tamashiro-cho, Tokushima 770
Japan
TITLE: Synthetic Approaches into Intensely Sweet Glycosides,
Baiyunoside and Osladin.
Afternoon
2:15 - 3:15 Paul L. Feldman
Glaxo Wellcome
Five Moore Drive
Research Triangle Park
N C 27709
U S A
TITLE: Organic Chemistry Aiding Basic Biological Research:
Understanding Nitric Oxide Synthase.
THURSDAY, JANUARY 11
Morning
9:00 - 10:00 William Gerwick
College of Pharmacy
Oregon State University
Corvallis, OR 97331-3507
U S A
TITLE: Structure and Biosynthesis of Bioactive Lipopeptides
from Marine Blue-Green Algae.
10:30 - 11:30 George A. Ellestad
American Cyanamid Co.
Pearle River, N Y 10966
U S A
TITLE: Recent Studies on the Mechanism of Action of
Calicheamicin.
Afternoon
FRIDAY, JANUARY 12
Morning
9:00 - 10:00 Franz Oesch
Institute of Toxicology
University of Mainz
Obere Zahlbacher StraBe 67
D-6500 Mainz
Germany
TITLE: (TO BE ANNOUNCED)
10:30 - 11:30 Tom J. Simpson
Department of Chemistry
University of Bristol
Cantocks Close
Bristol BS8 1TS
United Kingdom
TITLE: Polyketide Chain Assembly - Problems and Solutions.
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DAILY SCHEDULE
MONDAY, JANUARY 8
Morning
8:00 - 8:30 Completion of Registration
8:30 - 9:30 Opening Ceremony
9:30 - 9:40 Announcements
Chairman: Prof W R Chan
9:40 - 10:00 Coffee Break
10:00 - 11:00 Plenary Lecture
David G.I. Kingston - Fun and Games with
Taxol: New and Old Reactions of a Complex
Natural Product.
11:00 - 11:10 Question and Discussion Period
11:10 - 12:10 Chris Abell - Mechanistic Studies on
Biosynthetic Enzymes
12:10 - 12:20 Question and Discussion Period.
Afternoon
Chairman: Prof S McLean
2:00 - 3:00 Plenary Lecture
J -L. Wolfender - Strategies in the Search for
New Bioactive Plant Constituents
3:00 - 3:10 Question and Discussion Period.
3:10 - 3:30 Paper #1
*Kurt Wagschal, Y. Yoshizawa, D.J. Witter,
Y. Liu and J.C. Vederas - Biosynthesis of the
Hypocholesterolemic Polyketides ML-226C and
Compactin by Penicillum aurantiogriseum and
Lovastatin by Aspergillus terreus:
Determination of the Origin of Carbon,
Hydrogen and Oxygen Atoms by C13 NMR.
3:30 - 3:45 Coffee Break
3:45 - 4:05 Paper #2
Kuniaki Tatsuta - Total Synthesis and
Chemical Design of Useful Glycosidase
Inhibitors.
4:05 - 4:25 Paper #3
*Peter L. Ruddock and P.B. Reese - The Scope
and Limitations of the Reaction of
Mercury(II) Trifluoroacetate with D-Steriods.
Afternoon Cont'd
4:25 - 4:45 Paper #4
Philip Lowden - Studies on the Biosynthesis
of Rapamycin.
4:45 - 4:55 Paper #5
Const. Gletos - Rapamycin: An Extraordinary
Recovery from fermentation Broth.
4:55 - 5:05 Question and Discussion Period.
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TUESDAY, JANUARY 9
Morning
Chairman: Dr Baldwin Mootoo
9:00 - 10:00 Plenary Lecture
William F Reynolds - Multi-Dimensional NMR
Studies of Natural and Synthetic Products.
10:00 - 10:10 Question and Discussion Period.
10:10 - 10:25 Coffee Break
10:25 - 11:25 Plenary Lecture
Mugio Nishizawa - Synthetic Approaches into
intensely Sweet Glycosides Baiyunoside and
Osladin.
11:25 - 11:35 Question and Discussion Period.
11:35 - 11:55 Paper #6
*Augusto Rodriquez, J. Gabriel Garcia,
T. Kaimari and J. Hass - Intramolecular
Reactions of [3]-Cumulenes.
11:55 - 12:15 Paper #7
*Michael A Lyon and Y. Jackson - The Synthesis
of Analogues of Kuanoniamine A.
12:15 - 12:25 Question and Discussion Period.
Afternoon
Chairman: Prof Kuniaki Tatsuta
2:15 - 3:15 Plenary Lecture
Paul L. Feldman - Organic Chemistry Aiding
Basic Biological Research: Understanding
Nitric Oxide Synthase.
3:15 - 3:25 Question and Discussion Period
3:25 - 3:40 Coffee Break
3:40 - 4:00 Paper #8
*James M. Cook and T. Gan - Studies Directed
Toward Enantiospecific Synthesis of the
Antiamoebic Alkaloid Macrocarpamine and
10-Methoxymacrocarpamine.
4:00 - 4:20 Paper #9
*Laszlo v. Szentpaly and I.L. Shamovsky -
Modelling Intercalated PAH Metabolites:
Explanation for the Stereochemical and Shape
Selectivity of B-DNA for Bay-Region
Carcinogens.
4:20 - 4:40 Paper #10
*Bernard J. Rawling and P.R. James - Probing
the Mechanism of Action of Amphotericin B.
4:40 - 5:00 Paper #11
*John W. Huffman and S. Yu - A Probe for the
Cannabinoid Receptor: Synthesis of Deoxy
HU-210.
5:00 - 5:10 Question and Discussion Period.
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THURSDAY, JANUARY 11
Morning
Chairman: Prof. James Cook
9:00 - 10:00 Plenary Lecture
William Gerwick - Structure and Biosynthesis
of Bioactive Lipopeptides from Marine
Blue-Green Algae
10:00 - 10:10 Question and Discussion Period
10:10 - 10:25 Coffee Break
10:25 - 11:25 Plenary Lecture
George A. Ellestad - Recent Studies on the
Mechanism of Action of Calicheamicin.
11:25 - 11:35 Question and Discussion Period.
11:35 - 11:55 Paper #12
Annabel Cutter - Studies on the Biosynthesis
of Erythromycin.
11:55 - 12:15 Paper #13
12:15 - 12:35 Paper #14
Richard Franck - The Cycloaddition Way to
Glycosyl Transfer.
12:35 - 12:45 Question and Discussion Period.
Afternoon
Chairman: Prof Augusto Rodriquez
2:00 - 3:00 Plenary Lecture
K. Hostettmann - Strategies in the Search for
New Bioactive Plant Constituents
3:00 - 3:10 Question and Discussion Period
3:10 - 3:25 Coffee Break
3:25 - 3:45 Paper #15
Wolfgang Kraus - Biologically Active
Constituents of Tropical and Subtropical
Plants
3:45 - 4:05 Paper #16
*Roy B Porter and P.B. Reese - Secondary
Metabolites from Hyptis verticillata.
4:05 - 4:25 Paper #17
*Joanna M. Harris and J.C. Vederas - Synthesis
of Chiral Azodicarboxylate Esters and
Azodicarboxamides: Electrophilic Amination of
Achiral Enolates.
4:25 - 4:45 Paper #18
*Nicholas J. Lawrence and Simon W. Beeden -
2'-Desacetoxyaustropicatine from the Stem
Bark of Taxus Baccata: A Good Starting
Material for the Synthesis of Bioactive
Taxoids?
4:45 - 4:55 Question and Discussion Period.
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FRIDAY, JANUARY 12
Morning
Chairman: Prof John Huffman
9:00 - 10:00 Plenary Lecture
Franz Oesch - (Title to be announced)
10:00 - 10:10 Question and Discussion Period
10:10 - 10:30 Coffee Break
10:30 - 11:30 Plenary Lecture
Tom J. Simpson - Polyketide Chain Assembly -
Problems and Solutions.
11:30 - 11:40 Question and Discussion Period
11:40 - 12:00 Closing Ceremony.
back to top| ABELL, C. (P) | HARRIS, J. | NICELY, P. |
| BAMFORD, S. | HOLDER, A. | NISHIZAWA, M. (P) |
| CHAN, W. | HOLZBAUR, I. | OESCH, F. (P) |
| COOK, J. | HOSTETTMANN, K. | ONAKUNLE, O.A. |
| CONSTANTIN, B. | HUFFMAN, J. | PERRY, D. |
| CUTTER, A. | JARRETT, S. | RAWLINGS, B. |
| DANIEL, D. | KINGSTON, D.G.I. (P) | REYNOLDS, W.F. (P) |
| DRYSDALE, N. | KRAUS, W. | RODRIQUES, A. |
| DUCKI, S. | LAWRENCE, N. | SIMPSON, T.J. (P) |
| ELLESTAD, A.E. (P) | LOWDEN, P. | SUNDARAMOORTHI, R. |
| FELDMAN, P.L. (P) | MAXWELL, A. | TATSUTA, K. |
| FLYNN, D.L. | MCLEAN, S. | TINTO, W. |
| FRANCK, R. | MOOTOO, B. | WAGSCHAL, K. |
| GERWICK, W. (P) | MORGAN, T. | WILSON, D. |
| NEWTON, A. | WOLFENDER, J. -L. (P) |
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