Research Interests
1. Medicinal Plants. Plants, mainly from
the family Labiatae, Scrophulariaceae and Capparaceae families,
are being examined to isolate and characterise the major natural
products. Identification of metabolites with biological activity
is an integral part of this project.
2. Microbial transformations. Natural
products of agricultural and pharmaceutical interest are
structurally modified by selected strains of fungi in an effort
to produce a range of new analogues with enhanced
bioactivity.
3. Steroids. Partial synthesis of steroid
hormones is studied with the aim of identifying cheaper routes to
the production of these costly biochemicals.
Selected publications
- R.B.R. Porter, W.A. Gallimore and P.B. Reese, "Steroid
Transformations with Exophiala jeanselmei var.
lecaniicorni and Ceratocystis paradoxa,"
Steroids, 1999, 64, 770-779.
- M.R. Wilson, W.A. Gallimore and P.B. Reese, "Steroid
Transformations with Fusarium oxysporum f. sp.
cubense and Colletotrichum musae," Steroids,
1999, 64, 834-843.
- G.O. Buchanan, L.A.D. Williams and P.B. Reese,
"Biotransformation of Cadinane Sesquiterpenes by Beauveria
bassiana ATCC 7159," Phytochemistry, 2000, 54, 39-45.
- D. Burns, W.F. Reynolds, G. Buchanan, P.B. Reese and R.G.
Enriquez, "Assignment of 1H and 13C Spectra and Investigation of
Hindered Side Chain Rotation in Lupeol Derivatives," Magn. Reson.
Chem., 2000, 38, 488-493.
- D.O. Collins, W.A. Gallimore, W.F. Reynolds, L.A.D. Williams
and P.B. Reese, "New Skeletal Sesquiterpenoids, Caprariolides A -
D, from Capraria biflora and their insecticidal
activity," J. Nat. Prod., 2000, 63, 1515-1518.
- P.B. Reese, "Remote Functionalization Reactions in Steroids,"
Steroids, 2001, 66, 481-497.
- A.R.M. Chen and P.B. Reese, "Biotransformation of Terpenes
from Stemodia maritima by Aspergillus niger
ATCC 9142," Phytochemistry, 2002, 59, 57-62.
- D.O. Collins, W.F. Reynolds and P.B. Reese, "New Cembranes
from Cleome spinosa," J. Nat. Prod., 2004, 67,
179-183.
- G.D.A. Martin, W.F. Reynolds and P.B. Reese, "Investigation
of the importance of the C-2 oxygen function in the
transformation of stemodin analogues by Rhizopus oryzae
ATCC 11145," Phytochemistry, 2004, 65, 701-710.
- P.L.D. Ruddock, D.J. Williams and P.B. Reese, "The reactions
of palladium(II), thallium(III) and lead(IV) trifluoroacetates
with 3 b -acetoxyandrost-5-en-17-one; crystal structure of the
first trifluoroacetate bridged 5,6,7- p -allyl steroid palladium
dimer," Steroids, 2004, 69, 193-199.
Copyright © 2009 by Prof. P. B. Reese, all
rights reserved.
Return to
Chemistry, UWI-Mona, Home Page
Created and maintained by Prof. Robert J.
Lancashire,
The Department of Chemistry, University of the West Indies,
Mona Campus, Kingston 7, Jamaica.
Created February 1995. Last modified 4th January 2009
URL http://wwwchem.uwimona.edu.jm/chpr.html