18TH MONA SYMPOSIUM - JANUARY 3 - 7, 2000
SCIENTIFIC PROGRAMME
PLENARY LECTURES
MONDAY, JANUARY 3
Morning
10:30 - 11:30 Richard J. K. Taylor
Department of Chemistry
University of York
Heslington, York
United Kingdom YO10 5DD
TITLE: The Synthesis of Manumycin
Antibiotics.
Afternoon
2:00 - 3:00 Jin Cha
Department of Chemistry
University of Alabama
P.O. Box 870336
Tuscaloosa, AL 35487-0336
USA
TITLE: Small Ring-mediated Organic Synthesis.
3:25 - 4:25 Viresh H. Rawal
Department of Chemistry
University of Chicago
5735 South Ellis Avenue
Chicago, IL 60637
USA
TITLE: New Methods and Strategies for Complex
Molecule Synthesis.
TUESDAY, JANUARY 4
Morning
9:00 - 10:00 John P. N. Rosazza
College of Pharmacy
University of Iowa
115 S. Grand Ave.
Iowa City, IA 52242
USA
TITLE: Bacterial Nitric Oxide Synthase: Substrates,
Inhibitors and GTP Metabolites.
10:25 - 11:25 Gary W. Ashley
Kosan Biosciences, Inc.
3832 Bay Center Place
Hayward, CA 94545
USA
TITLE: New Drugs from Genetic Engineering of
Natural Product Pathways.
Afternoon
2:15 - 3:15 A. Douglas Kinghorn
College of Pharmacy
University of Illinois at Chicago
833 South Wood Street
Chicago, IL 60612
USA
TITLE: Plant Constituents with Potential Use in
Combatting Cancer.
THURSDAY, JANUARY 6
Morning
9:00 - 10:00 J. Stephen Clark
Department of Chemistry
The University
Nottingham
United Kingdom NG7 2RD
TITLE: New Reactions and Strategies for Marine
Natural Product Synthesis.
10:25 - 11:25 William H. Fenical
Scripps Institution of Oceanography
University of California
La Jolla, CA 92093
USA
TITLE: Marine Microorganisms, a New Source of
Chemical Diversity.
Afternoon
2:00 - 3:00 Masahiko Yamaguchi
Faculty of Pharmaceutical Sciences
Tohoku University
Aoba, Sendai 980-8578
Japan
TITLE: Chemistry of Optically Active Compounds
Containing Helicene.
3:25 - 4:25 Gordon Cragg
Natural Products Branch
National Cancer Institute
Frederick, MD 21702-1201
USA
TITLE: Natural Products Drug Discovery at the
National Cancer Institute.
Past Achievements and New Directions for the New Millenium.
FRIDAY, JANUARY 7
Morning
9:00 - 10:00 Motoo Tori
Faculty of Pharmaceutical Sciences
Tokushima Bunri University
Yamashiro-cho
Tokushima 770-8514
Japan
TITLE: Reductive Cyclizations into Hydrindanones
using Samarium(II) Iodide.
Synthetic Studies toward Coronafacic Acid and Botrydial.
10:25 - 11:25 Christopher J. Moody
School of Chemistry
University of Exeter
Exeter
United Kingdom EX4 4QD
TITLE: Synthesis of Thiopeptide Antibiotics.
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DAILY SCHEDULE
MONDAY, JANUARY 3
Morning
8:30 - 9:00 Completion of Registration
9:00 - 10:00 Opening Ceremony and Announcements
Chairman: Professor Baldwin Mootoo
10:00 - 10:30 Coffee Break
10:30 - 11:30 Plenary Lecture #1
Richard Taylor - The Synthesis of Manumycin
Antibiotics.
11:30 - 11:40 Question and Discussion Period
11:40 - 12:00 Short Paper #1
Richard Franck - Synthesis of a C-Glycoside
Analog of an Antiproliferative Glycolipid
via the Ramberg-Backlund Reaction.
12:00 - 12:20 Short Paper #2
Caroline Cox - Synthesis of 5- and
6-Chloropyridyl-substituted 2-Azabicyclo[2.2.1]heptanes;
Novel Epibatidine Isomers.
12:20 - 12:30 Question and Discussion Period
Afternoon
Chairman: Professor Richard Franck
2:00 - 3:00 Plenary Lecture #2
Jin Cha - Small Ring-mediated Organic
Synthesis.
3:00 - 3:10 Question and Discussion Period
3:10 - 3:25 Coffee Break
3:25 - 4:25 Plenary Lecture #3
Viresh Rawal - New Methods and Strategies for
Complex Molecule Synthesis.
4:25 - 4:35 Question and Discussion Period
4:35 - 4:55 Short Paper #3
James Cook - Enantiospecific Synthesis of
Tryptophan and Tryprostatins via the Schöllkopf
Chiral Auxiliary.
4:55 - 5:15 Short Paper #4
Karla-Sue Marriott - Synthesis of Rotenonoids and
Azarotenonoids.
5:15 - 5:25 Question and Discussion Period
TUESDAY, JANUARY 4
Morning
Chairman: Dr. Basil Burke
9:00 - 10:00 Plenary Lecture #4
Jack Rosazza - Bacterial Nitric Oxide Synthase:
Substrates, Inhibitors and GTP Metabolites.
10:00 - 10:10 Question and Discussion Period
10:10 - 10:25 Coffee Break
10:25 - 11:25 Plenary Lecture #5
Gary Ashley - New Drugs from Genetic Engineering
of Natural Product Pathways.
11:25 - 11:35 Question and Discussion Period
11:35 - 11:55 Short Paper #5
William Reynolds - NMR Assignments and
Investigation of Hindered Side Chain Rotation
in Lupeol Derivatives.
11:55 - 12:15 Short Paper #6
Wolfgang Kraus - Isolation and Structure
Determination of Biologically Active Plant
Constituents using Online LC Bioassay, LC-NMR and LC-MS
Techniques.
12:15 - 12:25 Question and Discussion Period
Afternoon
Chairman: Dr. Anderson Maxwell
2:15 - 3:15 Plenary Lecture #6
Douglas Kinghorn - Plant Constituents with
Potential Use in Combatting Cancer.
3:15 - 3:25 Question and Discussion Period
3:25 - 3:40 Coffee Break
3:40 - 4:00 Short Paper #7
Mike Antoun - The Flora of Puerto Rico as a
Potential Source of Bioactives.
4:00 - 4:20 Short Paper #8
Karen Nelson - Implications of Genomic Sequencing
for Health, Biotechnology and the Environment.
4:20 - 4:30 Question and Discussion Period
4:30 - 5:30 Poster Session
SYMPOSIUM IN HONOUR OF PROFESSOR WOLFGANG
KRAUS
THURSDAY, JANUARY 6
Morning
Chairman: Professor James Cook
9:00 - 10:00 Plenary Lecture #7
Stephen Clarke - New Reactions and Strategies for
Marine Natural Product Synthesis.
10:00 - 10:10 Question and Discussion Period
10:10 - 10:25 Coffee Break
10:25 - 11:25 Plenary Lecture #8
William Fenical - Marine Microorganisms, a New
Source of Chemical Diversity.
11:25 - 11:35 Question and Discussion Period
11:35 - 11:55 Short Paper #9
John Huffman - Synthesis and Pharmacology of a
Hybrid Cannabinoid.
11:55 - 12:15 Short Paper #10
Andrew Matthews - Synthesis and Study of
Polyamine-sterol Conjugates
Structurally Related to Squalamine.
12:15 - 12:25 Question and Discussion Period
Afternoon
Chairman: Professor John Huffman
2:00 - 3:00 Plenary Lecture #9
Masahiko Yamaguchi - Chemistry of Optically Active
Compounds Containing Helicene.
3:00 - 3:10 Question and Discussion Period
3:10 - 3:25 Coffee Break
3:25 - 4:25 Plenary Lecture #10
Gordon Cragg - Natural Products Drug Discovery at
the National Cancer Institute.
Past Achievements and New Directions for the New Millenium.
4:25 - 4:35 Question and Discussion Period
4:35 - 4:55 Short Paper #11
Greg Buchanan - An Insecticidal Sesquiterpene from
Hyptis verticillata.
4:55 - 5:15 Short Paper #12
Dwight Collins - Four Isomeric Sesquiterpenes from
Capraria biflora.
5:15 - 5:25 Question and Discussion Period
FRIDAY, JANUARY 7
Morning
Chairman: Professor Winston Tinto
9:00 - 10:00 Plenary Lecture #11
Motoo Tori - Reductive Cyclizations
into Hydrindanones using Samarium(II) Iodide.
Synthetic Studies toward Coronafacic Acid and
Botrydial.
10:00 - 10:10 Question and Discussion Period
10:10 - 10:25 Coffee Break
10:25 - 11:25 Plenary Lecture #12
Chris Moody - Synthesis of Thiopeptide
Antibiotics.
11:25 - 11:35 Question and Discussion Period
11:35 - 11:50 Closing Ceremony
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